Process for the preparation of pharmaceutical compositions comprising febuxostat in the form of tablets
The invention relates to a process for the preparation of pharmaceutical compositions comprising the steps of: a.1) mixing or blending powders comprising febuxostat and at least one pharmaceutically acceptable excipient in solid form using convection mixers or blenders at least until a homogeneous m...
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Format: | Patent |
Sprache: | eng ; fre ; ger |
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Zusammenfassung: | The invention relates to a process for the preparation of pharmaceutical compositions comprising the steps of:
a.1) mixing or blending powders comprising febuxostat and at least one pharmaceutically acceptable excipient in solid form using convection mixers or blenders at least until a homogeneous mixture is obtained, optionally mixing or blending the previous mixture with further excipients in solid form; or alternatively
a.2) mixing or blending powders comprising febuxostat with at least one disintegrating agent in solid form until a homogeneous mixture is obtained, optionally mixing or blending the previous mixture with further excipients in solid form, wherein the w/w % of disintegrating agents is not lower than 8 % of the pharmaceutical composition; and
b) compressing the mixture of step (a) into tablets. |
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