GENOME ASSEMBLY

The invention generally relates to methods for assembling sequence contigs. In certain embodiments, methods of the invention involve converting sequence contigs into maps, generating a plurality of single molecule restriction maps, aligning single molecule restriction maps to ends of the maps of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HENKHAUS, JOHN, K, ANANTHARAMAN, THOMAS, SWEENEY, DEACON, XIAO, NIANQING, PTASHKIN, RYAN, NATHAN, ZHU, BIN
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention generally relates to methods for assembling sequence contigs. In certain embodiments, methods of the invention involve converting sequence contigs into maps, generating a plurality of single molecule restriction maps, aligning single molecule restriction maps to ends of the maps of the sequence contigs, thereby producing extended sequence contigs, and aligning extended sequence contigs.