QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS

The invention provides certain quinoxalines and aza-quinoxalines of the Formula (I), and their pharmaceutically acceptable salts, wherein J1, J2, R1, R2, R3, R22, Ra, Rb, Rc, Rd, X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compound...

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Bibliographische Detailangaben
Hauptverfasser:	QIN, Jun, BROWN, William Colby, BOYCE, Christopher W, PALANI, Anandan, JIANG, Qin, RAO, Ashwin Umesh, MCCORMIC, Kevin D, ZHANG, Hongjun, BIJU, Purakkattle Johny, METHOD, Joe Lee, SILIPHAIVANH, Phieng, HUANG, Xianhai, VACCARO, Henry M, KELLEY, Elizabeth Helen, GAUUAN, Jolicia Polivina, XIAO, Dong, DHONDI, Pawan K, WU, Jie, CHEN, Xiao, LEYHANE, Andrew J, MAZZOLA, Robert D., Jr, DONG, Li, DEGRADO, Sylvia Joanna, YU, Younong, FEVRIER, Salem, ASLANIAN, Robert George
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides certain quinoxalines and aza-quinoxalines of the Formula (I), and their pharmaceutically acceptable salts, wherein J1, J2, R1, R2, R3, R22, Ra, Rb, Rc, Rd, X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.