Use of A-ring aromatic acetyl minocycline and pharmaceutical preparations derived from same for treatment and prevention of inflammation, autoimmune disorders and rejection of transplants

Use of A-ring aromatized acetyl minocycline compounds (I) for treating T cell-mediated diseases, is claimed. Use of A-ring aromatized acetyl minocycline compounds of formula (I) for treating T cell-mediated diseases, is claimed. R1-R5 : acetyl or H, where at least one of R1-R5 is acetyl. An independent claimS included for a pharmaceutical composition comprising A-ring aromatized acetyl minocycline compounds (I) and a pharmaceutical acceptable carrier. [Image] ACTIVITY : Antiallergic; Immunosuppressive. Test details are described but no results for the compounds of the claims are given. MECHANISM OF ACTION : None given. Die vorliegende Erfindung betrifft die Verwendung von A-Ringaromatisierten ein- oder mehrfachacetylierten Minocyclinen zur Behandlung und Prophylaxe von T-Zell-vermittelten Erkrankungen z. B. Autoimmunerkrankungen.