1-(Pyridin-2-yl)-3-(quinolin-4-yl)urea derivatives and related compounds as glycogen synthase kinase 3 (GSK-3) inhibitors for the treatment of neurodegenerative diseases

The present invention relates to novel heterocyclic compounds of formula I wherein the variables are as defined in the claims or the description, which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), compositions containing the compounds, their use for preparing a medicament for the tr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: VAN GAALEN, Marcel, HORNBERGER, Wilfried, TURNER, Sean, Colm, BAKKER, Margaretha, Henrica, Maria, HOFT, Carolin, MACK, Helmut
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to novel heterocyclic compounds of formula I wherein the variables are as defined in the claims or the description, which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), compositions containing the compounds, their use for preparing a medicament for the treatment of a medical disorder susceptible to the treatment with a compound that modulates, preferably inhibits, the activity of glycogen synthase kinase 3 , and methods of treatment of medical disorders susceptible to treatment with a compound that modulates glycogen synthase kinase 3 activity using the compounds.