COMPOUNDS AND THEIR USE

COMPOUNDS AND THEIR USE

Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as beta-lact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PERIASAMY, Hariharan, BALASUBRAMANIAN, Gopalan, PAUL-SATYASEELA, Maneesh, NARAYANAN, Shridhar, UDAYAMPALAYAM PALANISAMY, Senthilkumar, APPU, Aravind, MANICKAM, Senthilnathan
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as beta-lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors of beta-lactamases. These compounds restore/potentiate the activities of beta-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detecting beta-lactamases. Formula (I)