PHARMACEUTICAL COMPOSITION COMPRISING BICARBONATE SALT, AND USE THEREOF AS A MEDICAMENT IN THE TREATMENT AND/OR PREVENTION OF URINARY LITHIASIS AND RELATED DISEASES

A solid oral pharmaceutical composition in the form of at least one tablet, the tablet consisting of a core including at least one bicarbonate salt as active ingredient and at least one prolonged-release matrix, and of a coating including at least one coating agent, the composition allowing continuo...

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Bibliographische Detailangaben
Hauptverfasser: GUITTET, Catherine, ROUSSEL-MAUPETIT, Caroline, GRANIER, Luc-André
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A solid oral pharmaceutical composition in the form of at least one tablet, the tablet consisting of a core including at least one bicarbonate salt as active ingredient and at least one prolonged-release matrix, and of a coating including at least one coating agent, the composition allowing continuous release in vivo over a period from after a quarter of an hour and up to twelve hours after taking a single dose, for use thereof as a medicament, in particular in the treatment and/or prevention of urinary lithiasis and related diseases, occurring at a physiological pH and/or during urinary acidosis and/or during hypobicarbonataemia and/or during hypocitraturia and/or during hypercalciuria and/or during hyperoxaluria.