Angiostatin chimeras and uses thereof

The invention relates to a chimeric fusion protein comprising angiostatin releasable therefrom by cleaving a protease-sensitive site comprised therein, wherein the fusion protein comprises a protease. Further the invention provides related nucleic acids, vectors and host cells, as well as uses as me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KELLER-PINTER, ANIKO, SZILAK, LASZLO, TIMAR, JOZSEF, LETOHA, TAMAS, KATONA, ROBERT
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a chimeric fusion protein comprising angiostatin releasable therefrom by cleaving a protease-sensitive site comprised therein, wherein the fusion protein comprises a protease. Further the invention provides related nucleic acids, vectors and host cells, as well as uses as methods involving said chimeric protein.