Evaluation of co-registered images of differently stained tissue slices

A method for co-registering images of tissue slices stained with different biomarkers displays a first digital image of a first tissue slice on a graphical user interface such that an area of the first image is enclosed by a frame. Then a portion of a second image of a second tissue slice is display...

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Bibliographische Detailangaben
Hauptverfasser: SCHMIDT, GUENTER, ATHELOGOU, MARIA, SCHOENMEYER, RALF, BINNIG, GERD, ELLENBERG, PETER
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A method for co-registering images of tissue slices stained with different biomarkers displays a first digital image of a first tissue slice on a graphical user interface such that an area of the first image is enclosed by a frame. Then a portion of a second image of a second tissue slice is displayed such that the area of the first image enclosed by the frame is co-registered with the displayed portion of the second image. The displayed portion of the second image has the shape of the frame. The tissue slices are both z slices of a tissue sample taken at corresponding positions in the x and y dimensions. The displayed portion of the second image is shifted in the x and y dimensions to coincide with the area of the first image that is enclosed by the frame as the user shifts the first image under the frame.