Pharmaceutical composition containing an N-phenylpyrazole derivative, use for the preparation of a topical veterinary drug for flea control

Liquid pharmaceutical composition (I) comprises: 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile (fipronil); benzyl alcohol (at least 5 wt./vol.%); and an organic solvent (at least 50 wt./vol/.%) comprising propylene glycol monomethyl ether,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	Derrieu, Guy
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRAPPING
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Beschreibung
Zusammenfassung:	Liquid pharmaceutical composition (I) comprises: 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile (fipronil); benzyl alcohol (at least 5 wt./vol.%); and an organic solvent (at least 50 wt./vol/.%) comprising propylene glycol monomethyl ether, dipropylene glycol n-butyl ether, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, diethylene glycol monoethyl ether and/or propylene glycol, provided that (I) is free of alcohol 1-4C alcohol. ACTIVITY : Antiparasitic. MECHANISM OF ACTION : None given.