PYRAZINE DERIVATIVES AS INHIBITORS OF THE ENZYME SCD-1 FOR THE TREATMENT OF CANCER DISEASES AND DIABETES

The present invention relates to compounds having general formula I characterized in that wherein in particular: R1 represents one or a plurality of groups such as: trifluoromethyl, halogen such as F, Cl, Br, methyl, nitro. R represents nitrogen T-U represents C C, V represents N, W represents C O,...

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Bibliographische Detailangaben
Hauptverfasser: JUNQUERO, DIDIER, DUPONT-PASSELAIGUE, ELISABETH, MIALHE, SAMUEL, VALEILLE, KARINE, LEROY, ISABELLE
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to compounds having general formula I characterized in that wherein in particular: R1 represents one or a plurality of groups such as: trifluoromethyl, halogen such as F, Cl, Br, methyl, nitro. R represents nitrogen T-U represents C C, V represents N, W represents C O, R2 represents Cl or H, R3=H and R4=Me, A represents wherein n=m=1, X represents -CH2- and E represents -CH-, and D represents oxygen, along with the various isomers and mixtures thereof in any proportions, and the pharmaceutically acceptable salts thereof.