Mammal sestrins in the treatment of muscle wasting

The invention discloses a mammal sestrin product applicable in muscle atrophy, as well as any recombinant construction (vectors) comprising this mammal sestrin. A non-human animal model of muscle cell hypertrophy is also disclosed. In particular, the invention proposes tools for the treatment of atr...

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Bibliographische Detailangaben
Hauptverfasser: LUIS SERRANO, ANTONIO, MUNOZ CANOVES, PURIFICACION, PERDIGUERO SANTAMARIA, EUSEBIO, SOUSA CORADO VICTOR, PEDRO MIGUEL, RAYA CHAMORRO, MARINA
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention discloses a mammal sestrin product applicable in muscle atrophy, as well as any recombinant construction (vectors) comprising this mammal sestrin. A non-human animal model of muscle cell hypertrophy is also disclosed. In particular, the invention proposes tools for the treatment of atrophies of any aetiology, such as muscular dystrophies, cachexia, and atrophy related to malnutrition or to immobilization.