A SUBSTITUTED PYRIMIDINE AS A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST

The present invention is directed to a 2,6-substituted-4-monosubstitutedamino-pyrimidine compound of formula (I): or an enantiomer thereof, or an ester prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a met...

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Hauptverfasser: STOKLOSA, GREGORY T, AGUIAR, JOACY C, SHUM, PATRICK WAI-KWOK, POLI, GREGORY B, ZHAO, ZHICHENG, HARRIS, KEITH JOHN, CHOI-SLEDESKI, YONG-MI, REILING, STEPHAN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention is directed to a 2,6-substituted-4-monosubstitutedamino-pyrimidine compound of formula (I): or an enantiomer thereof, or an ester prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by the administration of a pharmaceutically effective amount of such a compound.