Imatinib mesylate preparation procedure

The present invention concerns a procedure for the preparation of Imatinib mesylate having a content of residual solvents in compliance with ICH guidelines. In particular, the invention concerns a procedure for the preparation of Imatinib mesylate of formula (I): comprising the treatment of a suspen...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GRENDELE, ENNIO, GALVAGNI, MARCO
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention concerns a procedure for the preparation of Imatinib mesylate having a content of residual solvents in compliance with ICH guidelines. In particular, the invention concerns a procedure for the preparation of Imatinib mesylate of formula (I): comprising the treatment of a suspension of Imatinib mesylate in an organic solvent with a crusher/disperser comprising one or more stator combinations and one or more rotors.