A PHARMACEUTICAL COMPOSITION OF KILLED CELLS WITH SUBSTANTIALLY RETAINED IMMUNOGENICITY

This invention discloses the process for lyophilization of the treated cells which comprises the use of a solution containing Trehalose along with amphipathic polymer Polyvinylpyrrolidone. Further the invention discloses the process treating cancer cells, freezing, lyophilizing and reconstituting. I...

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Bibliographische Detailangaben
Hauptverfasser: DESAI, Nirav Manojkumar, KHAMAR, Bakulesh Mafatlal, MODI, Rajiv Indravadan, SINGH, Satinder
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:This invention discloses the process for lyophilization of the treated cells which comprises the use of a solution containing Trehalose along with amphipathic polymer Polyvinylpyrrolidone. Further the invention discloses the process treating cancer cells, freezing, lyophilizing and reconstituting. Immunomodulator treated dead, but intact cancerous cells were recovered, which can subsequently be used for cancer immunotherapy.