Recombinant expression of soluble Interferon

The present invention generally relates to the field of recombinant gene expression in host cells. In particular, the invention relates to a host cell for the recombinant expression of a mammalian interferon protein, said cell comprising (a) a functional endogenous trxB gene; and (b) an inactivated...

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Bibliographische Detailangaben
Hauptverfasser:	DIEDERICH, BETTINA, SCHILLING, RALF
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention generally relates to the field of recombinant gene expression in host cells. In particular, the invention relates to a host cell for the recombinant expression of a mammalian interferon protein, said cell comprising (a) a functional endogenous trxB gene; and (b) an inactivated endogenous gor gene. The invention further relates to the use of such host cells for the recombinant expression of an interferon protein. The invention also provides a method for the recombinant expression of a soluble interferon in a host cell.