LIQUID FORMULATIONS FOR LONG-ACTING ERYTHROPOIETIN CONJUGATE

Disclosed is a liquid formulation which allows long-acting EPO conjugates, that have improved in vivo duration and stability, to be stable when stored for a long period of time. It comprises a stabilizer composition characterized by buffer and mannitol. Being free of human serum albumin and other po...

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Bibliographische Detailangaben
Hauptverfasser: IM, Dae Seong, JUNG, Sung Youb, KWON, Se Chang, LIM, Chang Ki, KIM, Min Young, BAE, Sung Min
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed is a liquid formulation which allows long-acting EPO conjugates, that have improved in vivo duration and stability, to be stable when stored for a long period of time. It comprises a stabilizer composition characterized by buffer and mannitol. Being free of human serum albumin and other potential factors harmful to the body, the liquid formulation is free of concerns about viral infections and guarantees excellent storage stability to long-acting EPO conjugates.