USE OF A SPIROLIDE, ANALOGUES AND DERIVATIVES THEREOF FOR TREATING AND/OR PREVENTING PATHOLOGICAL CONDITIONS LINKED TO THE TAU AND BETA-AMYLOID PROTEINS

USE OF A SPIROLIDE, ANALOGUES AND DERIVATIVES THEREOF FOR TREATING AND/OR PREVENTING PATHOLOGICAL CONDITIONS LINKED TO THE TAU AND BETA-AMYLOID PROTEINS

The present invention is in the field of biomedicine. Specifically, it relates to the use of a spirolide compound with the chemical structure: for preparing a drug for the prevention and/or treatment of a pathology related to the increase in ²-amyloid protein and/or hyperphosphorylation of tau prote...

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Bibliographische Detailangaben
Hauptverfasser: VALE GONZALEZ, CARMEN, BOTANA LOPEZ, LUIS MIGUEL, ALONSO LOPEZ, EVA
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention is in the field of biomedicine. Specifically, it relates to the use of a spirolide compound with the chemical structure: for preparing a drug for the prevention and/or treatment of a pathology related to the increase in ²-amyloid protein and/or hyperphosphorylation of tau protein compared to control, where said spirolide compound is administered in the amount necessary to reach a concentration in the serum of equal to or less than 50 nM. The amount administered is preferably the amount necessary to reach a concentration in the serum of between 0.5 nM and 50 nM.