Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods

Compounds of formula (1b) are provided wherein R 1 , R 2 , R 2' , R 3 , R 3' , R 4 , R 4' , Y, X and R 5 are as defined herein. The compounds are inhibitors of dipeptidyl peptidase IV, and may be useful in the treatment of inter alia diabetes.

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Bibliographische Detailangaben
Hauptverfasser:	HAMANN, LAWRENCE G, O'CONNOR, STEPHEN, P
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of formula (1b) are provided wherein R 1 , R 2 , R 2' , R 3 , R 3' , R 4 , R 4' , Y, X and R 5 are as defined herein. The compounds are inhibitors of dipeptidyl peptidase IV, and may be useful in the treatment of inter alia diabetes.