SPECIFIC NON COMPETITIVE PEPTID AND PEPTIDOMIMETIC MODULATORS OF THE GLYCOPROTEIN P

The invention relates to a compound having structure (I), which acts as a non-competitive specific inhibitor of P-glycoprotein (P-gp for Pleiotropic glycoprotein) and which can be used as a drug, particularly for improving the effectiveness of chemotherapy treatments. The invention is therefore suit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	ETTOUATI, LAURENT, ARNAUD, OPHELIE, FALSON, PIERRE, KOUBEISSI, ALI, PARIS, JOELLE, DI PIETRO, ATTILIO
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a compound having structure (I), which acts as a non-competitive specific inhibitor of P-glycoprotein (P-gp for Pleiotropic glycoprotein) and which can be used as a drug, particularly for improving the effectiveness of chemotherapy treatments. The invention is therefore suitable for use in the medical field, particularly for the chemotherapeutic treatment of cancers or infections.