BIOMARKERS FOR PREDICTING THE SENSITIVITY AND RESPONSE OF PROTEIN KINASE CK2-MEDIATED DISEASES TO CK2 INHIBITORS

BIOMARKERS FOR PREDICTING THE SENSITIVITY AND RESPONSE OF PROTEIN KINASE CK2-MEDIATED DISEASES TO CK2 INHIBITORS

Disclosed are biomarkers for determining the sensitivity of protein kinase CK2-mediated diseases, such as proliferative and/or inflammatory disorders, to treatment with CK2 inhibitors. These biomarkers can be used to predict or select subjects likely to be responsive to treatment with a CK2 inhibito...

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Bibliographische Detailangaben
Hauptverfasser: LIM, JOHN, K., C, PADGETT, CLAIRE, S, SIDDIQUI-JAIN, ADAM, ANDERES, KENNA, HO, CAROLINE, B, DRYGIN, DENIS, BLIESATH, JOSHUA, R, O'BRIEN, SEAN, VONHOFF, DANIEL, D, RICE, WILLIAM G
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Zusammenfassung:Disclosed are biomarkers for determining the sensitivity of protein kinase CK2-mediated diseases, such as proliferative and/or inflammatory disorders, to treatment with CK2 inhibitors. These biomarkers can be used to predict or select subjects likely to be responsive to treatment with a CK2 inhibitor, and to treat or monitor subjects undergoing treatment with a CK2 inhibitor.