Aminoheteroaryl compounds as protein kinase inhibitors

Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.

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Bibliographische Detailangaben
Hauptverfasser:	FUNK, LEE A, BOTROUS, IRINY, KUNG, PEI-PEI, LI, XIAOYUAN (SHARON), WALTER, ALLISON, BHUMRALKAR, DILIP, MENG, JERRY JIALUN, ZHANG, JENNIFER, NAMBU, MITCHELL DAVID, LIN, JASON (QISHEN), ZHANG, FANG-JIE, CHU, JI YU, HANAU, CATHLEEN ELIZABETH, CUI, JINGJONG, JEAN, KOLODZIEJ, STEPHEN, A, TRAN-DUBE, MICHELLE, NELSON, CHRISTOPHER G, JOHNSON, JOANNE, PAIRISH, MASON ALAN, SHEN, HONG
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.