Recombinant polyvalent vaccine

The problems to be solved by the present invention are to provide: a recombinant varicella-zoster virus; a process for producing the same; a pharmacological composition containing a recombinant varicella-zoster virus; a vector containing a BAC vector sequence in the specific gene of a genomic gene o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MORI, YASUKO, YOSHII, HIRONORI, TAKAHASHI, MICHIAKI, YAMANISHI, KOICHI, GOMI, YASUYUKI, SOMBOONTHUM, PRANEE
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The problems to be solved by the present invention are to provide: a recombinant varicella-zoster virus; a process for producing the same; a pharmacological composition containing a recombinant varicella-zoster virus; a vector containing a BAC vector sequence in the specific gene of a genomic gene of varicella-zoster virus; cells containing such a vector; a fragment capable of homologous recombination with a genome of varicella-zoster virus; a nucleic acid cassette containing the BAC vector sequence; and a multivalent vaccine. The above problems were solved by developing a process for producing a recombinant varicella-zoster virus, wherein the BAC vector sequence is inserted into a specific virus gene.