PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.

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Hauptverfasser: DEMATTEI, JOHN, RYAN, MICHAEL, P, ZLOKARNIK, GREGOR, NEUBERT-LANGILLE, BOBBIANNA, KRUEGER, BRIAN, R, VAN GOOR, FREDERICK, F, LOOKER, ADAM, R, GROOTENHUIS, PETER, D.J, TRUDEAU, MARTIN, YAP, DAHRIKA, MILFRED LAO, ROEPER, STEFANIE, BOTFIELD, MARTYN, C
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creator DEMATTEI, JOHN
RYAN, MICHAEL, P
ZLOKARNIK, GREGOR
NEUBERT-LANGILLE, BOBBIANNA
KRUEGER, BRIAN, R
VAN GOOR, FREDERICK, F
LOOKER, ADAM, R
GROOTENHUIS, PETER, D.J
TRUDEAU, MARTIN
YAP, DAHRIKA, MILFRED LAO
ROEPER, STEFANIE
BOTFIELD, MARTYN, C
description The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
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