PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.

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Bibliographische Detailangaben
Hauptverfasser: DEMATTEI, JOHN, RYAN, MICHAEL, P, ZLOKARNIK, GREGOR, NEUBERT-LANGILLE, BOBBIANNA, KRUEGER, BRIAN, R, VAN GOOR, FREDERICK, F, LOOKER, ADAM, R, GROOTENHUIS, PETER, D.J, TRUDEAU, MARTIN, YAP, DAHRIKA, MILFRED LAO, ROEPER, STEFANIE, BOTFIELD, MARTYN, C
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.