Apparatus and platform for multiplex analysis

The design and performance of an analytical apparatus and correspondingly designed microarray platform devices for facilitated multiplex analysis of analytes in liquids are disclosed. The apparatus in combination with the microarray platform devices are designed for performing bioanalytical assays a...

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Bibliographische Detailangaben
Hauptverfasser: HEITGER, FRIEDRICH, CHAI-GAO, HUI, CREVOISIER, FRANCOIS, SIGRIST, HANS
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The design and performance of an analytical apparatus and correspondingly designed microarray platform devices for facilitated multiplex analysis of analytes in liquids are disclosed. The apparatus in combination with the microarray platform devices are designed for performing bioanalytical assays and for detecting the presence of organic molecular analytes, optionally in microarray format. Several microarray platform devices, including one or several channel-type reaction chambers can be simultaneously analyzed. In preferred aspects, microarray platform devices are laminated microstructured microarray platforms, providing integrated channel-based reaction chambers having capture molecules printed and immobilized in open channel structures prior to lamination. Said microstructured microarray platforms are designed for use in conjunction with the apparatus leading to short assay times, low reagent volumes and performance at temperatures above, and differing from ambient.