Method for detecting mutation in Exon 12 of JAK2 gene, and nucleic acid probe and kit therefor

A probe for detecting a polymorphism in exon 12 of the JAK2 gene, the probe comprising at least one of the oligonucleotides in (a) to (c) below: (a) an oligonucleotide having a nucleotide sequence homologous to the sequence complementary to a nucleotide sequence having a length of 19 to 50 nucleotid...

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1. Verfasser: KOMORI, MARIKO
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A probe for detecting a polymorphism in exon 12 of the JAK2 gene, the probe comprising at least one of the oligonucleotides in (a) to (c) below: (a) an oligonucleotide having a nucleotide sequence homologous to the sequence complementary to a nucleotide sequence having a length of 19 to 50 nucleotides containing the nucleotides 114 to 132 of SEQ ID NO:1; (b) an oligonucleotide having a nucleotide sequence homologous to the sequence complementary to a nucleotide sequence having a length of 22 to 50 nucleotides containing the nucleotides 122 to 143 of SEQ ID NO:1; and (c) an oligonucleotide having a nucleotide sequence homologous to a nucleotide sequence having a length of 10 to 50 nucleotides containing the nucleotides 41 to 50 of SEQ ID NO:11.