PTK-7 protein involved in breast cancer

The present invention relates to the polypeptide PTK7 and the use thereof as a therapeutic target specifically in the treatment of triple negative (ER-, HER2-, PgR-) breast cancer cells. Further provided are agents which interact with and modulate the oncogenic activity of PTK7 as well as methods fo...

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Bibliographische Detailangaben
Hauptverfasser:	KNYAZEV, PJIOTR, GAERTNER, SILVIA, ULLRICH, AXEL, GAUTSCH, RENATE, KNYAZEVA, TATJANA DR
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the polypeptide PTK7 and the use thereof as a therapeutic target specifically in the treatment of triple negative (ER-, HER2-, PgR-) breast cancer cells. Further provided are agents which interact with and modulate the oncogenic activity of PTK7 as well as methods for the identification of such agents.