Concentrated protein lyophilates, methods and uses

The invention provides, among other things, methods for making lyophilized compositions of high surface area that comprise a protein and that reconstitute quickly and efficiently to solution of high protein concentration with minimal formation, if any, of foam, effervescence, bubbles, turbidity, or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RICCI, MARGARET SPEED, KRISHNAN, SAMPATHKUMAR, LIN, HONG, PALLITTO, MONICA, CRAMPTON, SHON LEE, XIE, YONG, NAGLE, SAMANTHA, CAO, WENJIN
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention provides, among other things, methods for making lyophilized compositions of high surface area that comprise a protein and that reconstitute quickly and efficiently to solution of high protein concentration with minimal formation, if any, of foam, effervescence, bubbles, turbidity, or particulates that might be deleterious.