Efficient surface plasmon resonance based protease assay

The present invention concerns an efficient surface plasmon resonance (SPR) protease assay which can be used for detect a protease activity in a media. The assay can be used for screen protease inhibitor or monitor biomarker activity. The high degree of efficiency of this assay is based on an innova...

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Bibliographische Detailangaben
Hauptverfasser:	YAHIAOUI, FARID, PETIT, SERGE
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention concerns an efficient surface plasmon resonance (SPR) protease assay which can be used for detect a protease activity in a media. The assay can be used for screen protease inhibitor or monitor biomarker activity. The high degree of efficiency of this assay is based on an innovative methodology, including the definition of an experimental strategy to improve assay efficiency by the use of a suitable couple antigen/antibody to improve the signal detection.