OXAZOLIDINON-QUINOLONE HYBRIDES AND INTERMEDIATES FOR THEIR PREPARATION

OXAZOLIDINON-QUINOLONE HYBRIDES AND INTERMEDIATES FOR THEIR PREPARATION

Oxazolidinyl- or dihydrofuranyl-substituted fluoro-benzene or -pyridine derivatives (ZP) are new. Oxazolidinyl- or dihydrofuranyl-substituted fluoro-benzene or -pyridine derivatives of formula (ZP) are new. [Image] U : N or CH; V : O, S or CR 6>R 7>; W : (hetero)cycloalkylene, (hetero)alkylcyc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SURIVET, JEAN PHILIPPE, SPECKLIN, JEAN-LUC, HUBSCHWERLEN, CHRISTIAN, BAESCHLIN, DANIEL K
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Oxazolidinyl- or dihydrofuranyl-substituted fluoro-benzene or -pyridine derivatives (ZP) are new. Oxazolidinyl- or dihydrofuranyl-substituted fluoro-benzene or -pyridine derivatives of formula (ZP) are new. [Image] U : N or CH; V : O, S or CR 6>R 7>; W : (hetero)cycloalkylene, (hetero)alkylcycloalkylene, (hetero)arylene, (hetero)aralkylene (all optionally substituted), bond, O, S or NR 8>; X : O or S; Y : group of formula (a) - (f); Z : alkylene, alkenylene, alkynylene, heteroalkylene, (hetero)cycloalkylene, (hetero)alkylcycloalkylene, (hetero)arylene or (hetero)aralkylene (all optionally substituted); R 8> : hydrogen, (hetero)alkyl, alkenyl, alkynyl, (hetero)aryl, (hetero)cycloalkyl, (hetero)alkylcycloalkyl, aralkyl or heteroaralkyl; and R 6>, R 7> : hydrogen, (hetero)alkyl, alkenyl, alkynyl, (hetero)aryl, (hetero)cycloalkyl, (hetero)alkylcycloalkyl, aralkyl, heteroaralkyl, halo, hydroxy, amino, nitro or thiol. [Image] ACTIVITY : Antibacterial. No details of tests are given. MECHANISM OF ACTION : None given in the source material.