5,7-DIHYDRO-6H-PYRIMIDO[5,4-D][1]BENZAZEPIN-6-THIONES AS PLK INHIBITORS

This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

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Bibliographische Detailangaben
Hauptverfasser: LI, GANG, BHARATHAN, INDU, T, VOS, TRICIA, J, GUO, JIANPING, REYNOLDS, DOMINIC, SOUCY, FRANCOIS, ELDER, AMY, M, DUFFEY, MATTHEW, O
Format: Patent
Sprache:eng ; fre ; ger
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