5,7-DIHYDRO-6H-PYRIMIDO[5,4-D][1]BENZAZEPIN-6-THIONES AS PLK INHIBITORS
This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
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| creator | LI, GANG BHARATHAN, INDU, T VOS, TRICIA, J GUO, JIANPING REYNOLDS, DOMINIC SOUCY, FRANCOIS ELDER, AMY, M DUFFEY, MATTHEW, O |
| description | This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders. |
| format | Patent |
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The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; ELECTROTHERAPY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MAGNETOTHERAPY ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; RADIATION THERAPY ; ULTRASOUND THERAPY</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160914&DB=EPODOC&CC=EP&NR=2373657B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160914&DB=EPODOC&CC=EP&NR=2373657B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI, GANG</creatorcontrib><creatorcontrib>BHARATHAN, INDU, T</creatorcontrib><creatorcontrib>VOS, TRICIA, J</creatorcontrib><creatorcontrib>GUO, JIANPING</creatorcontrib><creatorcontrib>REYNOLDS, DOMINIC</creatorcontrib><creatorcontrib>SOUCY, FRANCOIS</creatorcontrib><creatorcontrib>ELDER, AMY, M</creatorcontrib><creatorcontrib>DUFFEY, MATTHEW, O</creatorcontrib><title>5,7-DIHYDRO-6H-PYRIMIDO[5,4-D][1]BENZAZEPIN-6-THIONES AS PLK INHIBITORS</title><description>This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. 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The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY ELECTROTHERAPY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MAGNETOTHERAPY MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES RADIATION THERAPY ULTRASOUND THERAPY |
| title | 5,7-DIHYDRO-6H-PYRIMIDO[5,4-D][1]BENZAZEPIN-6-THIONES AS PLK INHIBITORS |
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