USIRNA COMPLEXES

This invention provides oligomer structures for therapeutic agents, the oligomers composed of one or more UNA nucleomonomers, along with nucleic acid monomers. The UNA oligomers may be used as therapeutic agents for treating or preventing disease. The UNA oligomers can be capable of modulating or si...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VAISH, Narendra, K, HOUSTON, Michael, E, TEMPLIN, Michael, V, POLISKY, Barry, A
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:This invention provides oligomer structures for therapeutic agents, the oligomers composed of one or more UNA nucleomonomers, along with nucleic acid monomers. The UNA oligomers may be used as therapeutic agents for treating or preventing disease. The UNA oligomers can be capable of modulating or silencing gene expression, through RNA interference or other modalities, and may have an antisense strand and a sense strand.