METHOD FOR SELECTIVELY CRYSTALLIZING A Z ISOMER OF IOPROMIDE

METHOD FOR SELECTIVELY CRYSTALLIZING A Z ISOMER OF IOPROMIDE

The present invention relates to a method for selectively crystallizing Z isomer of iopromide of formula (I) comprising a) dissolving a crude iopromide comprising a mixture of E and Z isomers or a concentrate thereof in an alcohol, and b) heating the resulting alcohol solution to obtain crystalline...

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Hauptverfasser: KIM, Wol-Young, CHOI, Soo-Jin, LEE, Byung-Goo, LIM, Young-Mook, LEE, Han-Kuk, LEE, Joon-Hwan
Format: Patent
Sprache:eng ; fre ; ger
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator KIM, Wol-Young
CHOI, Soo-Jin
LEE, Byung-Goo
LIM, Young-Mook
LEE, Han-Kuk
LEE, Joon-Hwan
description The present invention relates to a method for selectively crystallizing Z isomer of iopromide of formula (I) comprising a) dissolving a crude iopromide comprising a mixture of E and Z isomers or a concentrate thereof in an alcohol, and b) heating the resulting alcohol solution to obtain crystalline of Z isomer of iopromide; and a method for preparing a composition comprising the crystalline Z isomer of iopromide.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title METHOD FOR SELECTIVELY CRYSTALLIZING A Z ISOMER OF IOPROMIDE
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