METHOD FOR SELECTIVELY CRYSTALLIZING A Z ISOMER OF IOPROMIDE

METHOD FOR SELECTIVELY CRYSTALLIZING A Z ISOMER OF IOPROMIDE

The present invention relates to a method for selectively crystallizing Z isomer of iopromide of formula (I) comprising a) dissolving a crude iopromide comprising a mixture of E and Z isomers or a concentrate thereof in an alcohol, and b) heating the resulting alcohol solution to obtain crystalline...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KIM, Wol-Young, CHOI, Soo-Jin, LEE, Byung-Goo, LIM, Young-Mook, LEE, Han-Kuk, LEE, Joon-Hwan
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to a method for selectively crystallizing Z isomer of iopromide of formula (I) comprising a) dissolving a crude iopromide comprising a mixture of E and Z isomers or a concentrate thereof in an alcohol, and b) heating the resulting alcohol solution to obtain crystalline of Z isomer of iopromide; and a method for preparing a composition comprising the crystalline Z isomer of iopromide.