Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors

Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obse...

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Hauptverfasser:	RUMFELT, SHANNON, SHAM, KELVIN, CHEN, NING, DEMORIN, FRENEL FILS, ALLEN, JENNIFER R, HARRINGTON, PAUL, KALLER, MATTHEW R, MONENSCHEIN, HOLGER, RZASA, ROB, BISWAS, KAUSTAV, CHAVEZ, FRANK, JR, HORNE, DAN, YAO, GUOMIN, FROHN, MIKE, KUNZ, ROXANNE, REICHELT, ANDREAS, FALSEY, JAMES R, PICKRELL, ALEX, HU, ESSA, NGUYEN, TOM
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.