NOVEL VECTORS FOR PRODUCTION OF INTERFERON

Novel compositions for the production of interferons such as interferon-α 2a, interferon-α 2b, or interferon- 1a (IFN-α 2a, IFN-α 2b, or IFN- 1a) are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes an interferon su...

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Bibliographische Detailangaben
Hauptverfasser: COOPER, RICHARD, K, FIORETTI, WILLIAM, C
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Novel compositions for the production of interferons such as interferon-α 2a, interferon-α 2b, or interferon- 1a (IFN-α 2a, IFN-α 2b, or IFN- 1a) are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes an interferon such as IFN-α 2a, IFN-α 2b, or IFN- 1a, and the vectors comprising these components. In certain embodiments, these vectors are transposon-based vectors. Also provided are methods of making these compositions and methods of using these compositions for the production of an interferon such as IFN-α 2a, IFN-α 2b, or IFN- 1a.