HYDROPHILIC MATERIAL, MEDICAL MATERIAL AND SUSTAINED RELEASE PHARMACEUTICAL MATERIAL

HYDROPHILIC MATERIAL, MEDICAL MATERIAL AND SUSTAINED RELEASE PHARMACEUTICAL MATERIAL

A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the ²-position of an ², ²-unsaturated carboxyl group of a (co)polymer compr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHI Dongjian, ONISHI Makoto, AKASHI Mitsuru, FUJITA Yotaro, MATSUSAKI Michiya
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the ²-position of an ², ²-unsaturated carboxyl group of a (co)polymer comprising an aromatic compound such as 4-hydroxycinnamic acid in which an aromatic ring is substituted by the ±, ²-unsaturated carboxyl group and one or more hydroxyl groups. In particular, a hydrophilic material having a nanoparticle size which is highly dispersible in water, can well migrate into the blood and is useful as a drug carrier, a medical material and a sustained drug release material.