Optical detection system for labelling-free high-sensitivity bioassays

Optical detection system for labelling-free high sensitivity bioassays, which comprises the use of optical characterization techniques that allow vertical interrogation in micrometric and sub-micrometric domains and also at least one vertical-interrogation biophotonic inteferometric or resonant cell, characterized in that said system further comprises at least: (i) an optical measuring system that comprises, in turn, and at least, one excitation source, optical means for detection of the signal originating from an optical head, and an optical head; and (ii) an element for the integration of multiple analytes, comprising, in turn, and at least, a plurality of fluid connections connected with the cells, and a substrate on which rest not only biosensitive cells but also the fluid connections. In said systems, said optical head is arranged in such a manner as to allow analysis in respect of each one of said biosensitive cells and the analytes contained therein.