Antigenic peptides derived from telomerase

This invention relates to proteins or peptides which elicit T cell mediated immunity, and to cancer vaccines and compositions for anti-cancer treatment comprising such proteins or peptide fragments. This invention also relates to pharmaceutical compositions comprising the proteins or peptides and me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GAUDERNACK, GUSTAV, MOELLER, MONA, SAETERDAL, INGVIL, GJERTSEN, MARIANNE KLEMP, ERIKSEN, JON AMUND, SAEBOEE-LARSEN, STEIN
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:This invention relates to proteins or peptides which elicit T cell mediated immunity, and to cancer vaccines and compositions for anti-cancer treatment comprising such proteins or peptide fragments. This invention also relates to pharmaceutical compositions comprising the proteins or peptides and methods for generating T lymphocytes capable of recognising and destroying tumour cells in a mammal. More specifically, a telomerase protein or peptide for use in a method of treatment or prophylaxis of cancer is provided. In a preferred embodiment, the method comprises generating a T cell response against telomerase.