9-SUBSTITUTED MINOCYCLINE COMPOUNDS

The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetr...

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Hauptverfasser: Ismail, Mohamed Y, Stapleton, Karen, Verma, Atul, Bowser, Todd, Warchol, Ted, Sheahan, Paul, Frechette, Roger, Honeyman, Laura, Bhatia, Beena, Dumornay, Jimmy, Hawkins, Paul, Nelson, Mark L, Rennie, Glen, Koza, Darrell, Viski, Peter, Liu, Gui
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.