FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF

Disclosed are novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group, pharmaceutically acceptable salts thereof, methods for preparing the same and pharmaceutical compositions containing the same. The oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone grou...

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Hauptverfasser: PARK, TAE KYO, BAEK, SUNG YOON, WOO, SUNG HO, PARK, HEE SOCK, CHO, YOUNG LAG, JO, SANG HUI, KIM, YONG ZU, PARK, JU HYUN, SONG, HO YOUNG, LEE, DAE YON, KIM, YEON OK, CHAE, SANG EUN, LEE, HYANG SOOK
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed are novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group, pharmaceutically acceptable salts thereof, methods for preparing the same and pharmaceutical compositions containing the same. The oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group or the pharmaceutically acceptable salts thereof can be effectively used for the treatment of thromboembolism and tumor as an anticoagulant based on the inhibition of factor Xa.