METHOD OF PRODUCING BICYCLO[3.1.0]HEXANE DERIVATIVE USING ENZYME

Provided are methods for producing compounds represented by the formulae (II), (III), (Xa) and (Xb) and salts thereof. The compounds are intermediates in the asymmetric synthesis of bicyclo[3.1.0]hexane derivatives useful as metabotropic glutamate receptor modulators.

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Bibliographische Detailangaben
Hauptverfasser: HIROTSUKA, MITSUAKI, OSHIDA, MOTOKO, KAMIYAMA, HIROAKI, ISHII, TAKAAKI, SASAKI, JOJI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided are methods for producing compounds represented by the formulae (II), (III), (Xa) and (Xb) and salts thereof. The compounds are intermediates in the asymmetric synthesis of bicyclo[3.1.0]hexane derivatives useful as metabotropic glutamate receptor modulators.