Method of reducing the viral and microbial load of pancreatin

Production of pancreatin comprises providing pancreatin in solid form with residual moisture (0-0.5 pts. wt.), and subjecting pancreatin to heat treatment at 84, preferably = 80[deg] C. The biological activity of treated pancreatin corresponds to >= 50% of the biological activity of untreated pan...

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Hauptverfasser: RAEMSCH, CHRISTIAN, KURFUERST, MANFRED, SCHRAEDER, THOMAS, MOEST, THOMAS
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Production of pancreatin comprises providing pancreatin in solid form with residual moisture (0-0.5 pts. wt.), and subjecting pancreatin to heat treatment at 84, preferably = 80[deg] C. The biological activity of treated pancreatin corresponds to >= 50% of the biological activity of untreated pancreatin. The viral infectiousness of pancreatin is reduced by factor of greater than 1 log 1 0in comparison with the viral infectiousness of pancreatin. ACTIVITY : None given. MECHANISM OF ACTION : None given.