IMDIZO [4. 5-B] PYRIDINE DERIVATIVES USED AS RAF INHIBITORS

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated patholog...

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Hauptverfasser: WENGLOWSKY, STEVEN, M, FENG, BAINIAN, REN, LI, MALESKY, KIM, HANSEN, JOSHUA, D, RUDOLPH, JOACHIM, GRINA, JONAS, AHRENDT, KATERI, A, YOUNG, WENDY, B, LAIRD, ELLEN, R, MATHIEU, SIMON, WEN, ZHAOYANG, NEWHOUSE, BRAD, MORENO, DAVID, A, BUCKMELTER, ALEXANDRE, J
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.