DEXLANSOPRAZOLE PROCESS AND POLYMORPHS

DEXLANSOPRAZOLE PROCESS AND POLYMORPHS

Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methy...

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Hauptverfasser: NEELAM, UDAYKUMAR, PEDDIREDDY, SUBBAREDDY, SIGALA, ASHOK, GANGULA, SRINIVAS, SHINDE, SACHIN, GULABRAO, MUDUNURU, SATISH VARMA, TUMMALA, ARJUNKUMAR, MANNE, NAGARAJU, KOLLA, NAVEEN, KUMAR, NAREDLA, ANITHA, BADDAM, SUDHAKAR, REDDY, PATIL, SUMEET, VISHWASRAO, TUMMIDI, MADHU, KIRAN
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.