Lipase variants for pharmaceutical use

The present invention relates to a lipase which (a) has at least 50% identity to the sequence of amino acids 1-269 of SEQ ID NO: 2; (b) has lipase activity; and which, (c) as compared to the sequence of amino acids 1-269 of SEQ ID NO: 2, comprises a substitution in position 163.

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Bibliographische Detailangaben
Hauptverfasser: LAMSA, MICHAEL, YAVER, DEBBIE, SVENDSEN, ALLAN, LARSEN, SIGNE, CHRISTENSEN, LARS LEHMANN HYLLING, SKJOET, MICHAEL, LUNDIN, NINA, GREGORY, PETER COLIN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a lipase which (a) has at least 50% identity to the sequence of amino acids 1-269 of SEQ ID NO: 2; (b) has lipase activity; and which, (c) as compared to the sequence of amino acids 1-269 of SEQ ID NO: 2, comprises a substitution in position 163.