TRAIL VARIANTS FOR TREATING CANCER

The present invention relates to the use of a mutant TRAIL protein to treat various cancers in mammals. The invention provides a variant TRAIL protein, which has superior selectivity for the death receptor 5, for treating a mammal diagnosed with cancer.

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Hauptverfasser: COOL, ROBBERT, HANS, QUAX, WILHELMUS, JOHANNES, MAHALINGHAM, DEVALINHAM, DE RUIJTER, MARIEKE, DUIKER, EVELIEN, WILMA, VAN DER SLOOT, ALBERT, MARTINUS, RODRIGUES DOS REIS, CARLOS, RICARDO, SZEGEZDI, EVA, DE JONG, STEVEN, SAMALI, AFSHIN, DE VRIES, EMMA, GEERTRUIDA, ELISABETH, SERRANO, LUIS
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creator COOL, ROBBERT, HANS
QUAX, WILHELMUS, JOHANNES
MAHALINGHAM, DEVALINHAM
DE RUIJTER, MARIEKE
DUIKER, EVELIEN, WILMA
VAN DER SLOOT, ALBERT, MARTINUS
RODRIGUES DOS REIS, CARLOS, RICARDO
SZEGEZDI, EVA
DE JONG, STEVEN
SAMALI, AFSHIN
DE VRIES, EMMA, GEERTRUIDA, ELISABETH
SERRANO, LUIS
description The present invention relates to the use of a mutant TRAIL protein to treat various cancers in mammals. The invention provides a variant TRAIL protein, which has superior selectivity for the death receptor 5, for treating a mammal diagnosed with cancer.
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language eng ; fre ; ger
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TRAIL VARIANTS FOR TREATING CANCER
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