TRAIL VARIANTS FOR TREATING CANCER

The present invention relates to the use of a mutant TRAIL protein to treat various cancers in mammals. The invention provides a variant TRAIL protein, which has superior selectivity for the death receptor 5, for treating a mammal diagnosed with cancer.

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Bibliographische Detailangaben
Hauptverfasser:	COOL, ROBBERT, HANS, QUAX, WILHELMUS, JOHANNES, MAHALINGHAM, DEVALINHAM, DE RUIJTER, MARIEKE, DUIKER, EVELIEN, WILMA, VAN DER SLOOT, ALBERT, MARTINUS, RODRIGUES DOS REIS, CARLOS, RICARDO, SZEGEZDI, EVA, DE JONG, STEVEN, SAMALI, AFSHIN, DE VRIES, EMMA, GEERTRUIDA, ELISABETH, SERRANO, LUIS
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to the use of a mutant TRAIL protein to treat various cancers in mammals. The invention provides a variant TRAIL protein, which has superior selectivity for the death receptor 5, for treating a mammal diagnosed with cancer.